Multi Domain Life Saving Trauma Innovations (MuLTI)

This RPP entitled “Multi domain Life Saving Trauma Innovations (MuLTI)” will support the development of highly innovative Materiel Products and new ways, methods, or modifications to existing trauma practice (i.e., Knowledge Products) for future Multi Domain Operations (MDO) where evacuation capabilities may be significantly delayed or unavailable, including decision support, semi-autonomous, and autonomous technologies. Projects should focus on enhancing capabilities at the point of greatest need, including life-saving interventions to be rendered immediately post-injury, during periods of prolonged care in theater, and during en route care within and from theater.  Encouraged characteristics of possible medical materiel solutions include, but are not limited to, concepts that address one or more of the following: mobility, low-weight and cube, low-power, modularity, interoperability, ruggedization, automation, low-complexity, decision supported, closed or semi-closed loop feedback, longer shelf life, temperature stability, low-complexity, regulatory pathway clarity, manufacturability, cost-savings, and/or life-cycle product sustainability.

The Joint Program Committee (JPC)-6/Combat Casualty Care Research Program (CCCRP) is one of six major Defense Health Program (DHP) core research program areas within the DHP medical Research, Development, Test, and Evaluation (RDT&E) programs. JPC-6 is a committee of Department of Defense (DoD) and non-DoD medical and military technical experts in combat casualty care-related program areas. Per the program’s mission statement, JPC-6/CCCRP seeks to drive medical innovation through development of knowledge and materiel solutions for the acute and early management of combat-related trauma on current and future battlefields; including point-of-injury, far-forward, prolonged, en route, and early facility based care. Innovations developed by JPC-6/CCCRP-supported research are applied in-theater across the echelons of care, and within the prehospital and critical care clinical facilities of the Military Health System. These solutions not only help to minimize the morbidity and mortality of combat-related injuries sustained by the Warfighter, they also are often translatable to civilian care. An excerpt from the CCCRP Vision Statement provides further illustration of the program’s needs:

“In responding to mid and long term guidance which is underscored by a predicted loss of air superiority, we must adapt our perspective and tactics with regard to casualty evacuation and the “golden hour” paradigm of OIF/OEF in order to continue to drive down case fatality and died of wound rates. There is a necessary paradigm shift away from transporting casualties to a damage control capability (ROC2/3) to more efficiently bringing “golden hour” medical assets and intervention capabilities to the point of injury.”
– Col Michael Davis, CCCRP Director (2017)

The JPC-6/CCCRP has identified three overarching focus areas for funding under the JPC-6/CCCRP MuLTI Program.

  • Focus Area #1 – Prolonged Field Care and En Route Care (PFC/ERC): The PFC/ERC portfolio seeks to provide materiel and knowledge solutions to enable increased levels of care closer to the point of injury, including care provided during evacuation, to provide patient care for longer time periods when delayed evacuation exceeds available capability and/or capacity, and to extend provider capabilities in order to care for larger numbers of casualties
  • Focus Area #2 – Battlefield Resuscitation and Immediate Stabilization of Combat Casualties (BRISCC): Hemorrhage is the leading cause of preventable deaths among combat casualties occurring before a medical treatment facility is reached. The BRISCC portfolio seeks to provide materiel and knowledge solutions to enable the immediate stabilization at the point of injury.  Current strategic objectives are to provide: (1) technologies to control bleeding in the pre-hospital environment, (2) safer, more effective, and more logistically supportable blood products, and (3) technologies and knowledge sets for improved damage control resuscitation.
  • Focus Area #3 – Neurotrauma & Traumatic Brain Injury (TBI): The Neurotrauma Portfolio (NTP) is focused on closing military-relevant gaps across a broad range of research areas to improve the prevention, diagnosis, management, and treatment of TBI and related sequelae from point-of-injury through recovery. The NTP’s goal is to decrease morbidity and mortality from neurotrauma, mitigate secondary brain injury across all TBI severities, and advance materiel and knowledge development to expand and develop new clinical practice guidelines, care algorithms, therapies, devices, and procedures that advance the decision-making capabilities of medical personnel, enabling earlier intervention and improved outcomes.

The research project award recipients were selected from the Offerors who responded to MTEC’s Request for Project Proposals (19-08-MuLTI).